Signosis基因功能分析,靶标发现和确认,分析开发以及化合物筛选通常需要基于细胞的分析。经过工程改造以通过转基因整合到宿主基因组中表达目的基因的稳定细胞系提供了进行此类分析的有效方法。然而,由于建立这种细胞系的过程繁琐,开发过程耗时,劳动,试剂和材料的昂贵以及单个克隆的转染后验证,是否值得仍然值得商de在单个实验室中开发这种稳定细胞系的方法。  为了促进研究,Signosi
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Description:Insulin resistance and central adiposity are strong risk indicators for type 2 diabetes and coronary heart disease. Insulin resistanceis apathologicalcondition in whichcellsfail to respond normally to the hormoneinsulin, leading tohigh bl...
2019-03-06 阅读量(10)
Description:Interleukin 12 (IL-12) is an interleukin that plays important roles in the activities of natural killer cells and T lymphocytes, the differentiation of naive T cells into Th1 cells, the growth and function of T cells, the production of in...
2019-03-11 阅读量(15)
Description:Cytokines are signaling molecules that have critical roles in many biological processes such as cellular growth, differentiation, gene expression, migration, immunity, and inflammation. Cytokines that are secreted from cells bind to cell-...
2019-03-20 阅读量(15)
Description:A set of miRNA complementary sequences have been engineered at 3 untranslated region of luciferase gene respectively to make a series of miRNA luciferse reporter vectors.When miRNA targets the binding site at 3UTR downstream of reporter l...
2019-03-21 阅读量(10)
Description:TF targets its binding site at upstream of TATA promoter to induce the expression of luciferase gene. It results in induction of luciferase enzyme activity. Through comparison of luciferase activity in two samples, up- or down-reguated TF...
2019-03-24 阅读量(16)
Description:TF targets its binding site at upstream of TATA promoter to induce the expression of luciferase gene. It results in induction of luciferase enzyme activity. Through comparison of luciferase activity in two samples, up- or down-reguated TF...
2019-04-03 阅读量(4)
Description:Tumour Necrosis Factor alpha (TNFa), is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. The pr...
2019-04-10 阅读量(14)
Description:Cytokines are extracellular signaling proteins produced by different cell types that act on target cells to modulate diverse cellular functions, such as recruiting specific cell types to the site of inflammation, increasing the activation...
2019-04-11 阅读量(3)
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