Signosis基因功能分析,靶标发现和确认,分析开发以及化合物筛选通常需要基于细胞的分析。经过工程改造以通过转基因整合到宿主基因组中表达目的基因的稳定细胞系提供了进行此类分析的有效方法。然而,由于建立这种细胞系的过程繁琐,开发过程耗时,劳动,试剂和材料的昂贵以及单个克隆的转染后验证,是否值得仍然值得商de在单个实验室中开发这种稳定细胞系的方法。  为了促进研究,Signosi
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2020-07-08 阅读量(17)
Description:When one TF is activated, it binds to a biotin-labeled probe, which is designed based on the consensus binding sequence of the TF. When the formed complex is subjected to electrophoresis, it runs slower than the free probe, and can be eas...
2020-07-04 阅读量(3)
Description:TF targets its binding site at upstream of TATA promoter to induce the expression of luciferase gene. It results in induction of luciferase enzyme activity. Through comparison of luciferase activity in two samples, up- or down-reguated TF...
2020-07-29 阅读量(6)
Description:The transforming growth factor beta 1 (TGF-ß1) gene codes a multifunctional cytokine that controls proliferation, differentiation, and other functions in many cell types, including cancer cells, the surrounding stromal cells, immune...
2020-08-07 阅读量(4)
Description:Stable cell lines are great tool for the study of gene regulation and cellular signaling pathways. Signosis over the last few years has successfully developed many different stable cell lines that are applicable for a wide range of resear...
2020-09-12 阅读量(35)
Description:miRNAs have been implicated in the regulation of various biological processes such as cell death and cell proliferation. They can act as oncogenes and tumor suppressor genes, playing a crucial role in tumorogenesis. The change in the expr...
2020-09-21 阅读量(32)
Description:A set of miRNA complementary sequences have been engineered at 3 untranslated region of luciferase gene respectively to make a series of miRNA luciferse reporter vectors.When miRNA targets the binding site at 3UTR downstream of reporter l...
2020-09-30 阅读量(32)
Description:A set of miRNA complementary sequences have been engineered at 3 untranslated region of luciferase gene respectively to make a series of miRNA luciferse reporter vectors.When miRNA targets the binding site at 3UTR downstream of reporter l...
2020-10-13 阅读量(47)
Description:Gene expression is regulated by individual cells, so why not study gene expression in a single cell such as stem cells, neurons, developmental tissues, and laser capture microsections? To allow researchers the ability to take on single ce...
2020-10-22 阅读量(19)
Description:Protein Standards for HumanER StressELISA Strip (EA-1141)
2020-10-31 阅读量(24)
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