Signosis基因功能分析,靶标发现和确认,分析开发以及化合物筛选通常需要基于细胞的分析。经过工程改造以通过转基因整合到宿主基因组中表达目的基因的稳定细胞系提供了进行此类分析的有效方法。然而,由于建立这种细胞系的过程繁琐,开发过程耗时,劳动,试剂和材料的昂贵以及单个克隆的转染后验证,是否值得仍然值得商de在单个实验室中开发这种稳定细胞系的方法。  为了促进研究,Signosi
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Description:When one TF is activated, it binds to a biotin-labeled probe, which is designed based on the consensus binding sequence of the TF. When the formed complex is subjected to electrophoresis, it runs slower than the free probe, and can be eas...
2018-11-05 阅读量(4)
Description:Granulocyte colony-stimulating factor (G-CSF) is a colony-stimulating factor hormone. It is produced by a number of different tissues to stimulate the bone marrow to produce granulocytes and stem cells and to stimulate the bone marrow to ...
2018-12-21 阅读量(6)
Description:When one TF is activated, it binds to a biotin-labeled probe, which is designed based on the consensus binding sequence of the TF. When the formed complex is subjected to electrophoresis, it runs slower than the free probe, and can be eas...
2019-01-03 阅读量(8)
Description:SMAD 1/5/8 Responsive Luciferase Reporter HEK293 Cell Line is derived human embryonic kidney, and stably express firefly luciferase reporter gene under the control of SMAD 1/5/8 response element. This cell line is an ideal cellular model ...
2019-01-06 阅读量(9)
Description:When one TF is activated, it binds to a biotin-labeled probe, which is designed based on the consensus binding sequence of the TF. When the formed complex is subjected to electrophoresis, it runs slower than the free probe, and can be eas...
2019-01-07 阅读量(2)
Description:The transforming growth factor beta 1 (TGF-ß1) gene codes a multifunctional cytokine that controls proliferation, differentiation, and other functions in many cell types, including cancer cells, the surrounding stromal cells, immune...
2019-01-11 阅读量(9)
Description:The vectors can be transfected into the corresponing cells for studying the function of a specific nuclear receptor, such as protein-protein interaction. Upon the vector transfects into the cells, the nuclear receptor is expressed with c-...
2019-01-14 阅读量(1)
Description:TF targets its binding site at upstream of TATA promoter to induce the expression of luciferase gene. It results in induction of luciferase enzyme activity. Through comparison of luciferase activity in two samples, up- or down-reguated TF...
2019-01-17 阅读量(5)
Description:The vectors can be transfected into the corresponing cells for studying the function of a specific nuclear receptor, such as protein-protein interaction. Upon the vector transfects into the cells, the nuclear receptor is expressed with c-...
2019-01-19 阅读量(1)
Description:Oxidative stress is caused by an imbalance in the generation and removal of reactive oxygen species (ROS).  ROS elicits a wide spectrum of responses, such as cell proliferation, growth arrest, or apoptosis. ROS comes mostly from the endog...
2019-01-20 阅读量(11)
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