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商品描述
| Source | M.W. | 406.48 | CAS No. | 1062368-24-4 | |
|---|---|---|---|---|---|
| Structural Info |  | ||||
| Formulation | Powder | ||||
| Reconstitution | Before reconstitution, werecommend a brief spin to drive down any material dislodged from the bottom ofthe tube. The compound is soluble inDMSO. | ||||
| Stability | The powder is stable for atleast 2 year if stored at -20 °C. The dissolved compound is stable for at least 1 month at 4 °C, butshould be stored in aliquots at -20 °C for longer term. Protect from light. | ||||
| Purity | Greater than 98% as determined by LC/MS analysis.LC/MS and/or NMR data available upon request. | ||||
| Biological Activity | |||||
| Country of Origin | USA | ||||
A selectiveinhibitor of bone morphogenetic protein (BMP) type I receptors (ALK-2and ALK-3). Only weakly inhibits ALK-4,-5, and -7. 4-[6-(4-Piperazin-1-yl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-yl]-quinolineRef: Cuny, G.D., et al. Structure-activityrelationship study of bone morphogenetic protein (BMP) signaling inhibitors.Bioorg Med Chem Lett 18: 4388-92, 2008.
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