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| Description | MTT,ayellowtetrazole,isreducedtopurpleformazaninlivingcells,andusedforassessingcellmetabolicactivity. |
|---|---|
| InVitro | MTTisusedinconjunctionwithrhodamineBtomeasuremitochondrialmembranepotential.MTT-formazanisgeneratedinmitochondriaactsasafluorescencequencherforrhodaminethatdistributesacrossmembranesofviablecellsaccordingtomembranepotential.IntheabsenceofmPMS,cellularreductionofMTTisstrong.MTTismembrane-impermeablewhenincorporatedintolargeunilamellarliposomes,andthereforeitistakenupbycellsviaendocytosis[1]. |
| ClinicalTrial | ViewMoreCollapse |
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Pleaserefertothesolubilityinformationtoselecttheappropriatesolvent. | ||||||||||||||||
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| MolecularWeight | 414.32 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Formula | C₁₈H₁₆BrN₅S | ||||||||||||
| CASNo. | 298-93-1 | ||||||||||||
| Storage |
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| Shipping | RoomtemperatureincontinentalUS;mayvaryelsewhere | ||||||||||||
| Solvent&Solubility | DMSO:≥32mg/mL;H2O:0.88mg/mL(Needultrasonicandwarming) *"<1 mg/ml"="" means="" slightly="" soluble="" or="" insoluble.="" "≥"="" means="" soluble,="" but="" saturation="">1> Purity:99.59%
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