Thisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
VEGFwasinitiallypurifiedfrommediaconditionedbynormalbovinepituitaryfolliculo-stellatecellsandbyavarietyoftransformedcelllinesasamitogenspecificforvascularendothelialcells.ThreemouseCDNAclones,whicharisethroughalternativesplicingandwhichencodematuremousemonomericVEGFhaving120,164,or188,aminoacids,respectively,havebeenidentified.Tworeceptortyrosinekinases(RTKs),Flt-1andFlk-1(themousehomologueofhumanKDR),bothmembersofthetypeIIIsubclassofRTKscontainingsevenimmunoglobulin-likerepeatsintheirextracellulardomains,havebeenshowntobindVEGFwithhighaffinity.VEGFhasbeenfoundtobeapotentangiogenesisinducerinvivo.

Specifications:

CatalogNo.	125-06
CountryofManufacture	UnitedStates
ProductCode	rmVEGF120
Size/Quantity	2μg
ProductUse	Thisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
Storage	Storeat-20°Cafterreceiving.UponReconstitution,storeat2-8°Cforuptooneweek.FormaximalstABIlity,aliquotandstoreat-20°C.Avoidrepeatedfreeze/thawcycles.
ShippingInfo	Dryice
Synonyms	VEGFA,VEGF-A,Vascularpermeabilityfactor(VPF),VEGF,Vegf188,Vegf164,Vegfa
AASequence	MAPTTEGEQKSHEVIKFMDVYQRSYCRPIETLVDIFQEYPDEIEYIFKPSCVPLMRCAGCCNDEALECVPTSESNITMQIMRIKPHQSQHIGEMSFLQHSRCECRPKKDRTKPEKCDKPRR
Source	Escherichiacoli
MolecularWeight	Approximately28.4kDadisulfide-linkedhomodimericproteinconsistingoftwo121aminoacidpolypeptidechains.
Purity	>96%bySDS-PAGEandHPLCanalyses.
BIOLOGicalActivity	Fullybiologicallyactive.TheED50is2-4ng/ml,asdeterminedbyHUVECcellproliferation.
PhysicalAppearance	Whitelyophilizedpowder.
Formulation	Lyophilizedfroma0.2μmfilteredsolutioninPBS,pH7.4.
Endotoxin
Reconstitution	Reconstituteinsteriledistilledwatercontaining0.1%BSAtoaconcentrationof0.1-1.0mg/mL.

SciencCell公司 是1999年成立于美国洛杉矶圣地亚哥，是一家快速成长的生物技术公司，其一直专注于是研发实验和治疗相关的细胞产品。ScienCell公司提供多种多样、高质量的人和动物的原代细胞，原代细胞培养基、干细胞研究相关领域产品和相关试剂。