Thisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
EGFwasoriginallydiscoveredincrudepreparationsofnervegrowthfactorpreparedfrommousesuBMAxillaryglandsasanactivitythatinducedearlyeyelidopening,incisoreruption,hairgrowthinhibition,andstuntingofgrowthwheninjectedintonewbornmice.EGFisapotentgrowthfactorthatstimulatestheproliferationofvariousepidermalandepithelialcells.Additionally,EGFhasbeenshowntoinhibitgastricsecretion,andtobeinvolvedinwoundhealing.EGFsignalsthroughareceptorknownasc-erbB,whichisaclassItyrosinekinasereceptor.ThisreceptoralsobindswithTGF-alphaandVGF(vacciniavirusgrowthfactor).

Specifications:

CatalogNo.	125-04
CountryofManufacture	UnitedStates
ProductCode	rmEGF
Size/Quantity	100μg
ProductUse	Thisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
Storage	Storeat-20°Cafterreceiving.UponReconstitution,storeat2-8°Cforuptooneweek.FormaximalstABIlity,aliquotandstoreat-20°C.Avoidrepeatedfreeze/thawcycles.
ShippingInfo	Dryice
Synonyms	Urogastrone,URG
AASequence	NSYPGCPSSYDGYCLNGGVCMHIESLDSYTCNCVIGYSGDRCQTRDLRWWELR
Source	Escherichiacoli
MolecularWeight	6.0kDa,asinglenon-glycosylatedpolypeptidechaincontaining53aminoacids,including3intramoleculardisulfide-bonds.
Purity	>96%bySDS-PAGEandHPLCanalyses.
BIOLOGicalActivity	Fullybiologicallyactive.TheED50is1x10^7units/mg.
PhysicalAppearance	Whitelyophilizedpowder.
Formulation	Lyophilizedfroma0.2μmfilteredsolutioninPBS,pH7.4.
Endotoxin
Reconstitution	Reconstituteinsteriledistilledwatercontaining0.1%BSAtoaconcentrationof0.1-1.0mg/mL.

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