Thisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
BasicFibroblastGrowthFactor(bFGF)isamemberoftheFGFfamilyofmitogenicpeptideswhichiscomprisedofatleast22proteinsshowing35-55%aminoacidsequenceconservation.UnlikeotherFGFfamilymembers,bFGFandacidicFGF(aFGF)lacksignalpeptidesandaresecretedviaadifferentmechanismotherthantheclassicalproteinsecretionpathway.Thepredicted17kDabFGFisoformcanbelocatedinboththecytoplasmandthenucleus.Theuseofalternativetranscriptionstartsiteswithinthegeneproducesseveraldifferentisoformsrangingfrom21-24kDaproteins.

Specifications:

CatalogNo.	124-02
CountryofManufacture	UnitedStates
ProductCode	rmbFGF
Size/Quantity	10μg
ProductUse	Thisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
Storage	Storeat-20°Cafterreceiving.UponReconstitution,storeat2-8°Cforuptooneweek.FormaximalstABIlity,aliquotandstoreat-20°C.Avoidrepeatedfreeze/thawcycles.
ShippingInfo	Dryice
Synonyms	FGF-2,FibroblastGrowthFactor-basic
AASequence	MPALPEDGGAAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHVKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTEECFFFERLESNNYNTYRSRKYSSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
Source	Escherichiacoli
MolecularWeight	Approximately16.2kDa,asinglenon-glycosylatedpolypeptidechaincontaining146aminoacids.
Purity	>98%bySDS-PAGEandHPLCanalyses.
BIOLOGicalActivity	Fullybiologicallyactive.TheED50is
PhysicalAppearance	Whitelyophilizedpowder.
Formulation	Lyophilizedfroma0.2μmfilteredsolutioninPBS,pH7.4.
Endotoxin
Reconstitution	Reconstituteinsteriledistilledwatercontaining0.1%BSAtoaconcentrationof0.1-1.0mg/mL.

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