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蚂蚁淘在线 / 品牌中心 / Sciencell / Sciencell/重组小鼠GM-CSF/122-03/1 Ea

Sciencell/重组小鼠GM-CSF/122-03/1 Ea

价格
￥1460.00
货号：122-03
浏览量：127
品牌：Sciencell
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商品描述
Thisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
GM-CSFwasinitiallycharacterizedasafactorthatcansupporttheinvitrocolonyformationofgranulocyte-macrophageProgenitors.Itisalsoagrowthfactorforerythroid,megakaryocyte,andeosinophilprogenitors.GM-CSFisproducedbyTcells,Bcells,macrophages,mastcells,endothelialcells,fibroblasts,andADIpocytesinresponsetocytokineorinflammatorystimuli.Onmaturehematopoieticcells,GM-CSFactsasaprosurvivalfactorandactivateseffectorfunctionsofgranulocytes,monocytes/macrophages,andeosinophils.ItpromotesaTh1biasedimmuneresponse,angiogenesis,allergicinflammation,andthedevelopmentofautoimmunity.The22kDaglycosylatedGM-CSF,similartoIL-3andIL-5,isacytokinewithacoreoffourαundled?-helices.MaturemouseGM-CSFshares49%-54%aminoacidsequenceidentitywithcanine,feline,human,andporcineGM-CSFand69%withratGM-CSF.TheactivityofGM-CSFisspeciesspecificbetweenhumanandmouse.MouseGM-CSFisonlyweaklyactiveonratcells,althoughratGM-CSFisfullyactiveonmousecells.

Specifications:

CatalogNo.122-03
CountryofManufactureUnitedStates
ProductCodermGM-CSF
Size/Quantity5μg
ProductUseThisproductisforresearchuseonly.Itisnotapprovedforuseinhumans,animals,orinvitrodiagnosticprocedures.
StorageStoreat-20°Cafterreceiving.UponReconstitution,storeat2-8°Cforuptooneweek.FormaximalstABIlity,aliquotandstoreat-20°C.Avoidrepeatedfreeze/thawcycles.
ShippingInfoDryice
SynonymsCSF-2,MGI-1GM,GM-CSF,Pluripoietin-alpha,Molgramostin,Sargramostim
AASequenceMAPTRSPITVTRPWKHVEAIKEALNLLDDMPVTLNEEVEVVSNEFSFKKLTCVQTRLKIFEQGLRGNFTKLKGALNMTASYYQTYCPPTPETDCETQVTTYADFIDSLKTFLTDIPFECKKPVQK
SourceEscherichiacoli
MolecularWeightApproximately14.2kDaglobularproteinconsistingof124aminoacidsresidues.
Purity>95%bySDS-PAGEandHPLCanalyses.
BIOLOGicalActivityFullybiologicallyactive.TheED50is?0.2ng/ml,correspondingtoaspecificactivityof?5x10^6units/mg,asdeterminedbymurineFDC-P1cellproliferation.
PhysicalAppearanceWhitelyophilizedpowder.
FormulationLyophilizedfroma0.2μmfilteredsolutioninPBS,pH7.4.
Endotoxin
ReconstitutionReconstituteinsteriledistilledwatercontaining0.1%BSAtoaconcentrationof0.1-1.0mg/mL.
SciencCell公司 是1999年成立于美国洛杉矶圣地亚哥，是一家快速成长的生物技术公司，其一直专注于是研发实验和治疗相关的细胞产品。ScienCell公司提供多种多样、高质量的人和动物的原代细胞，原代细胞培养基、干细胞研究相关领域产品和相关试剂。