TheCKAssaykitmeasuresCKactivityinvarioustypesofsamples,includingtissueandcelllysate.Thisproductisforresearchpurposesonlyandisnotapprovedforuseinanimals,humans,ordiagnosticprocedures.
Creatinekinase(CK)catalyzesthereversIBLephosphorylationofcreatinebyATPtoformphosphocreatineandADP.CKconsistsoftwosubunits:M(muscle)-andB(brain)-subunits,andhasthreeisoenzymes:CK-MM(foundinskeletalmuscle),CK-MB(foundincardiacmuscle),andCK-BB(foundinbrainandlung).Clinically,CKlevelsinbloodareusedtotestforthediagnosisand/ormonitoringofmyocardialinfraction(heartattack),rhaBDomyolysis(severemusclebreakdown),musculardystrophy,andacuterenalfailure,aselevatedCKactivitylevelsarecommontosuchdiseases.Inthiscolorimetricassay,CKconvertsphosphocreatineandADPtocreatineandATP,whereATPisthenusedforsubsequentenzyme-coupledreactionstoformNADPH.CKactivityisdeterminedbyassayingtherateofNADPHformation,whichisproportionaltothereductioninabsorbanceat340nmovertime(ΔOD340nm/min).

Specifications:

CatalogNo.	8618
CountryofManufacture	UnitedStates
ProductCode	CK
Size/Quantity	100Tests
ProductUse	TheCKAssaykitmeasuresCKactivityinvarioustypesofsamples,includingtissueandcelllysate.Thisproductisforresearchpurposesonlyandisnotapprovedforuseinanimals,humans,ordiagnosticprocedures.
Storage	Storein-20°C
ShippingInfo	Shippedondryice.

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