Specifications&Handling:

ProductData
Synonyms	NicotinamidePhosphoribosyltransferase;PBEF1;Pre-BCellColonyEnhancingFactor1;IntracellularNampt
Properties
ApplicationSet	QuantitativeELISA
Specificity	DetectshumanNampt.Weaklycross-reacts(<15%) with="" mouse="" nampt="" and="" rat="" nampt.="" does="" not="" cross-react="" with="" human="" adiponectin,="" human="" resistin,="" human="" relm-β="" or="" human="" leptin.="">
Crossreactivity	Human
Quantity	1x96wells
Sensitivity	30pg/ml
Range	0.25to16ng/ml
SampleType	CellLysate
AssayType	Sandwich
DetectionType	Colorimetric
ProductType	Kit
ShippingandHandling
Shipping	BLUEICE
ShortTermStorage	+4°C
LongTermStorage	+4°C
HandlingAdvice	Afterstandardreconstitution,preparealiquotsandstoreat-20°C.Avoidfreeze/thawcycles.Plateandreagentsshouldreachroomtemperaturebeforeuse.
Use/Stability	12monthsafterthedayofmanufacturing.SeeexpirydateonELISAKitbox.
Documents
Manual	Download
MSDS	Download
RelatedProducts
Nampt(Visfatin/PBEF)(human)ELISAKit Nampt(Visfatin/PBEF)(mouse/rat)DualELISAKit

Description:

Nicotinamidephosphoribosyltransferase(Nampt;pre-Bcellcolony-enhancingfactor;PBEF;Visfatin)isan52kDAadipokinesecretedbyadiposetissueandinvolvedinthebiosynthesisofnicotinamideadeninedinucleotide(NAD+).TwoformsofNamptexist,anintracellularform(iNampt)andanextracellularform(eNampt).WhilethefunctionofiNamptasanessentialandrate-limitingNAD+biosyntheticenzymeiswellestablished,thephysiologicalroleofeNamptisstillamatterofdebate.IthasbeenshownthatNamptexpressionisincreasedindifferentdiseases,likediabetes,obesity,fetalgrowthretardation,sepsis,inflammatoryboweldisease,Crohn’sdiseaseandrheumatoidarthritis.Furthermore,NamptmightbeaMarkerofpre-eclampsiaandofendothelialhealth.