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Description

ProductName	ProstaticAcidPhosphatase
Source	HumanSemen
CatalogueNumber	475-30
Purity	PartiallyPurified
Form	Lyophilized
Activity	5-15U/mgsolid(Dimension®ClinicalChemistrySystem)
Protein	>0.2protein/mg(Coomassie/Biuret)
SpecificActivity	Typically>30U/mgprotein
UnitDefinition	OneunitwillcatalyzethehydrolysisofonemicromoleofthymolphthaleinmonophosphatetothymolphthaleinandphosphateperminuteatpH5.6and37°C.
Ammonia	0.1μmole/mgsolid
Appearance	Off-whitepowder
Form	Lyophilizedfromsodiumcitrateandsodiumchloride,pH6.5
Recertification	3years
Storage	-20°C
Solubility	Clear,colorlesssolution(10mg/mLsaline)
Synonyms	ACP,PAP,AcidPhos,5-nucleotidase,5-NT,Ecto-5-nucleotidase,Thiaminemonophosphatase,TMPase,PAPf39
MolecularWeight	~100,000
CASNumber	9001-77-8
E.C.Number	3.1.3.2
Gene	ACPP,5-NT,ACP-3,ACP3,PAP
GeneID	55
AccessionNo	P15309

Applications

Controls/Calibrators/StandardsImmunoassaysClinicalChemistryAssayDevelopment/ValidationLifeScienceTumorMarkers

Overview

LeeBiosolutionsproduceshumansemenProstaticAcidPhosphatase(PAP,ACP)forresearchandbulkIVDdiagnosticmanufacturing.

LeeBiohasanextensivehumansemendonorprogram.CustomAcidPhosphatasepurificationondonorspecificsemenisavailable.

WhatisHumanAcidPhosphatase?HumanProstateAcidPhosphatasealsoknownashumanprostaticacidphosphatase(PAP,ACP)isalternativemarkertoProstateSpecificAntigen(PSA)forprostatemalignancy.RapeinvestigationswilloftenincludetestingforthepresenceofHumanprostaticacidphosphatase.

ProstaticAcidphosphatase(PAP)isaphosphatase,atypeofenzyme,usedtofreeattachedphosphategroupsfromothermoleculesduringdigestion.AcidPhosphataseisstoredinlysosomesandfunctionswhenthesefusewithendosomes,whichareacidifiedwhiletheyfunction;therefore,HumanAcidPhosphatasehasanacidpHoptimumbelow7.0.

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