Medimabs/FGFR1c、FGFR2b、FGFR2c、FGFR3b、FGFR3c、FGFR4人类重组抗体面板/6小瓶(每个20µg)/MM-0313

价格
¥13900.00
货号:MM-0313
浏览量:127
品牌:Medimabs
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商品描述
Target:
Human FGFR1c, FGFR2b, FGFR2c, FGFR3b, FGFR3c, FGFR4
Target background:
Fibroblast growth factor receptors (FGFRs) encompass a family of type I transmembrane tyrosine kinases, which undergo dimerization and phosphorylation after ligand binding. FGFRs are of therapeutic value given their involvement in tumourigenesis. Four distinct genes encoding closely related FGFRs, FGFR1‑4, have been identified. Alternatively-spliced variants that encode different protein isoforms of each of the 4 FGFR proteins include the following subset: FGFR1c, FGFR2b, FGFR2c, FGFR3b, FGFR3c and FGFR4. Using phage display technology, we identified specific binders against human targets that correspond to each of the above 6 isoforms. This FGFR family panel will allow researchers to profile each indicated FGFR isoform without cross-reacting to the other using Flow Cytometry and ELISA.
Immunogen:
ECD of recombinant protein (see individual product for more informations)
Specificity: This panel is made of 6 different antibodies in individual 20µg vials with no cross reactivities in between each isoforms tested. (see individual products for more informations)
Clone ID:
CR - 100 (generated by CCAB)
Isotype:
hIgG1; also available as mIgG1, scIgG1, schmIgG2a
Preservative:
None
Format:
Lyophilized protein A purified in PBS pH7.4; Antibody kit
Recommend starting dilution:
Reconstitute with deionized water. Optimal dilution has to be determined by the user.
Limitations:
Research Use Only; Manufactured by CCAB under a license using Life Technologies proprietary cell lines.
Storage:
Lyophilized antibodies can be kept at 4ºC for up to 3 months and should be kept at -20ºC for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80ºC) or kept at 4ºC for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.
MédiMabs将帮助您获得实验所需的多克隆抗体。从我们30天的最佳免疫方案到77天的经典免疫方案中选择免疫方案。我们还根据您选择的型号和时间表提供疫苗开发服务。多克隆抗体可用物种:小鼠,大鼠,豚鼠,山羊,鸡。抗原设计和表位预测定制肽合成,蛋白质生产或DNA优化免疫免疫接种亲和纯化Species.pngClassic_Classic.png经典协议:56天的实验方案,包括对2只兔子进行4次免疫,最终抽血(总共约90mL血清)77天的实验方案,包括对2只兔子进行5种免疫,在4次注射后进行测试流血(将进行ELISA滴定,样品将发送给您在测定分析中),最终流血(总共约90mL血清)  Optimmune Logo_Optimmune.png最佳协议:为了快速回答或获得概念证明,请选择或选择免疫方案。30天快速方案,包括3次注射1只兔子和Optimmune +佐剂,最后流血(总共约45mL血清)。缩短免疫以获得良好IgG反应的时间。血清净化全血清亲和纯化也可以作为我们所有多克隆抗体项目的附加服务提供。无论您的冰箱中已经有血清,还是想要在应用中或项目中获得更好的信号,我们都可以帮助您和免疫原亲和力纯化您的宝贵抗体。疫苗开发我们将与您一起设计抗原,并为您的项目找到最合适的动物模型和佐剂。该项目在经过认证的CCAC动物设施下进行,并拥有专业的员工。我们还可以通过我们的专业合作伙伴(Immuni T)为您提供触发免疫反应和免疫毒理学评估的完整评估。