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蚂蚁淘在线 / 品牌中心 / Enzo Life / Enzolifesciences/Nitrotyrosine monoclonal antibody (7A5)/ADI-905-763-100/100µg
商品描述
Product Specification:
| Clone: | 7A5 |
| Host: | Mouse |
| Isotype: | IgG1 |
| Immunogen: | KLH modified with Nitrotyrosine. |
| Species reactivity: | Human, Mouse, Rat Dog |
| Applications: | ELISA, WB |
| Recommended Dilutions/Conditions: | ELISA (0.05µg/ml) Western Blot (0.5µg/ml, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Purity Detail: | Thiophilic adsorption and size exclusion chromatography purified. |
| Formulation: | Lyophilized from 1ml of 2x PBS containing 0.09% sodium azide, PEG, and sucrose. |
| Reconstitution: | Reconstitute with 1ml water (15 minutes at room temperature). |
| Use/Stability: | Stable at -80°C up to 1 year, at 4°C up to 3 months. |
| Handling: | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | The enzymatic conversion of arginine to citrulline by nitric oxide synthase (NO Synthase) leads to the formation of nitric oxide (NO). Peroxynitrite is formed following reaction of NO with superoxide, producing a potent oxidant that reacts with a variety of biological molecules, including tyrosine residues in proteins. Tyrosine nitration can inactivate enzymes and receptors that depend on tyrosine residues for their activity. Nitration prevents phosphorylation of tyrosine residues important for signal transduction. |


