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蚂蚁淘在线 / 品牌中心 / Enzo Life / Enzolifesciences/15-deoxy-Δ12,14-PGJ2 polyclonal antibody/ADI-915-044-100/100µl
商品描述
ProductSpecification:
| AlternativeName: | 15-deoxy-Δ12,14-ProstaglandinJ2 |
| Host: | Rabbit |
| Immunogen: | 15-deoxy-Δ12,14-ProstaglandinJ2. |
| Speciesreactivity: | Speciesindependent |
| Applications: | ELISA |
| PurityDetail: | Sodiumsulfateprecipitationpurified. |
| Formulation: | Liquid.InPBScontaining1.0mg/mlRabbitIgGand0.1%sodiumazide. |
| Handling: | Avoidfreeze/thawcycles. |
| Shipping: | ShippedonBlueIce |
| LongTermStorage: | -20°C |
| ScientificBackground: | 15-deoxy-Δ12,14-ProstaglandinJ2(15-d-PGJ2)isoneoftheultimatedehydrationproductsofPGD2,formedviatheintermediateΔ12-PGJ2.15-d-PGJ2isphysiologicallypresentinbodyfluidsatconcentrationof10-12to10-9M,butincreasesdramaticallyunderstresssuchasinfectionandinflammation.15-d-PGJ2exertsbothpro-andanti-inflammatoryeffectsinacell-typeandconcentration-dependentmanner,withmanyoftheseeffectsmediatedviabindingtotheγisoformoftheperoxisomeproliferators-activatedreceptor(PPAR-γ).15-d-PGJ2appearstoinduceHO-1expressionbyaPPAR-γ-independentmechanismmediatedbythegenerationofreactiveoxygenspecies(ROS). |


