品牌分类
品牌咨询
- 北京泰泽瑞达成为荷兰Axon Medchem,中国地区独家代理商!将与Axon公司携...
- axon medchem代理上海 |产品详情
- AXONMEDCHEM
- axon medchem
- axon medchem
- ...Axon Medchem,中国地区独家代理商!将与Axon公司携手开拓中国市场...
- ...荷兰Axon Medchem,中国地区独家代理商!将与Axon公司携手开拓中国市 ...
- *** axon medchem进口采购 axon medchem一级代理[产品打印页面]
- REP 3123 dihydrochloride
- axon medchem|产品目录|代理商|蚂蚁淘原厂直采
- Axon Medchem | 领英
- 蚂蚁淘在线专注海外进口生物试剂原厂进口
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
AGI 6780
Axon 2274
CAS [1432660-47-3]
MF C21H18F3N3O3S2MW 481.51
- Purity:99%
- Soluble in DMSO

Description
Inhibitor of isocitrate dehydrogenases (IDH) selective for mutant IDH2.AGI 6780 potently and selectively inhibits the tumor-associated mutant IDH2/R140Q (EC50 value <20 nm="" for="" reduction="" of="" 2hg="" levels="" in="" cell="" lines)="" in="" an="" allosteric="" manner="" at="" the="" dimer="" interface,="" and="" induces="" differentiation="" of="" tf-1="" erythroleukemia="" and="" primary="" human="" acute="" myelogenous="" leukemia="" cells="" in="" vitro.="">20>
| F. Wang et al. Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. Science. 2013, 340, 622-626. |
- Certificate of Analysis
- Material Safety Data Sheet
Cell Signaling & OncologyDiabetes & MetabolismEpigeneticsEC 1.1.1.42Stem Cell DifferentiatorIDH
Potent and selective inhibitor of the tumor-associated mutant IDH2 (R140Q)
Chemical name
N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide
Parent CAS No.
[1432660-47-3]


