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25CN-NBOH hydrochloride - NBOH-2C-CN hydrochloride
Axon 2811
CAS [1539266-32-4]
MF C18H20N2O3.HClMW 348.82
- Purity:98%
- Soluble in water and DMSO

Description
25CN-NBOH is a highly selective and brain penetrant 5-HT2A receptor agonist (Ki value of 1.3 nM; EC50 value of 2.1 nM). Moreover, 25CN-NBOH was behaviorally active in two mouse models of hallucinogenic effects.
KEYWORDS: 25CN-NBOH hydrochloride | supplier | 5-HT2A agonist | NBOH-2C-CN hydrochloride | 25CN NBOH hydrochloride | 25CNNBOH hydrochloride | CAS [1539266-32-4] | [1391489-32-9] | Serotonin | 5-HT2A | Agonist | Receptors
| M Hansen et al. Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists. ACS Chem Neurosci. 2014 Mar 19;5(3):243-9. |
| WE Fantegrossi et al. Hallucinogen-like effects of 2-([2-(4-cyano-2,5-dimethoxyphenyl) ethylamino]methyl)phenol (25CN-NBOH),a novel N-benzylphenethylamine with 100-fold selectivity for 5-HT₂A receptors, in mice.Psychopharmacology (Berl). 2015 Mar;232(6):1039-47. |
| AA Jensen et al. Detailed Characterization of the In Vitro Pharmacological and Pharmacokinetic Properties of N-(2-Hydroxybenzyl)-2,5-Dimethoxy-4-Cyanophenylethylamine (25CN-NBOH),a Highly Selective and Brain-Penetrant 5-HT2A Receptor Agonist.J Pharmacol Exp Ther. 2017 Jun;361(3):441-453. |
- Certificate of Analysis
- Material Safety Data Sheet
Chemical name
4-(2-(2-Hydroxybenzylamino)ethyl)-2,5-dimethoxybenzonitrile hydrochloride
Parent CAS No.
[1391489-32-9]


