MD Biosciences/可的松多克隆抗体/100µl/2043002

价格
面议
货号:2043002
浏览量:127
品牌:MD Biosciences
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商品描述
  • Overview
  • Data/Specifications
  • Literature/Support

Overview

Overview:

Cortisone (17-hydroxy-11-dehydrocorticosterone) is a hormone produced by the adrenal glands located above the kidney. It is the inactive precursor molecule of the active hormone cortisol. Cortisone is released in response to stress and has anti-inflammatory properties. In medicine, it is used for the treatment of arthritis and allergies.

Data/Specifications

Data/Specifications:

Immunogen: Cortisone-BTGHost Animal: SheepFormat: Ig FractionIg Concentration: 7.2 mg/ml (U.V. abs @280 nm)Working Dilutions: 1.25 μg/ml (ELISA microtitre plate based)pH: 7.2Buffer: 20 mM Phosphate, 150 mM Sodium ChloridePreservative: 0.09% Sodium AzideStorage: -20 °C

Literature/Support

Literature/Support/Publications:

Cortisone Polyclonal Antibody (PDF)

MD Biosciences的ArthritoMab™抗体混合物是4种单克隆抗体的重组配方,可诱导关节炎,是广泛使用的胶原蛋白诱导的关节炎(CIA)模型的替代品。小鼠的许多转基因株系都在C57BL / 6背景上。然而,该菌株对CIA或CAIA诱导的关节炎均难治。传统上,为了克服这一点,在CAIA模型中,增加了抗体混合物的剂量。这种重新配制的抗体混合物经过优化,可在C57BL / 6中产生关节炎,并以较低剂量的抗体诱导关节炎。这种新配方还可以用于传统上需要大量鸡尾酒的其他小鼠品系。