$39.50 – $365.00

ITSE AF cell culture media supplement replaces blood-derived insulin transferrin supplements that contain serum-derived transferrin

Product Description

ITSE AF is a recombinant insulin and transferrin cell culture 100x media supplement. ITSE AF contains 4 components that are typically required for optimal cell growth in serum-free or reduced serum media. Insulin has cell signaling functions and promotes the uptake of glucose and amino acids. Transferrin is a universal source of iron for cells that is non-toxic carrier of iron and reduces the generation of toxic free-radicals and peroxide. Selenium is required for the activity of glutathione peroxidase, thioredoxin reductase, and other antioxidant enzymes. Ethanolamine is a phospholipid precursor that improves the performance of cells in serum-free media and is required for the growth of some cell types.

Advantages

• Manufactured in the United States, in a tertiary-level, animal component-free, ISO 9001 certified facility
  • Raw materials, manufacturing equipment, and packaging is certified animal-free
  • Host manufacturing system is of non-animal and non-human source
  • Complete supply and manufacturing chain is owned and operated by InVitria
• Supplied as a 100x sterile liquid
• Blood-free components improve performance consistency in media
• Cost-effective

InVitria诸如牛胎血清（FBS），牛和人血清白蛋白以及牛和人转铁蛋白等动物成分已在许多生物过程中成为流行成分，但由于担心，科学家于1990年代开始寻找去除血清和其他动物产品的方法有关产品质量，安全性和动物管理的信息。动物产品是不受欢迎的，因为它们具有传播诸如agents病毒（疯牛病）和病毒（HIV）之类的传染因子的风险。此外，动物成分和血液来源的产品不确定，导致批次间差异很大。由于这些原因，美国食品药品管理局（FDA），欧洲药品管理局（EMA）和其他监管机构不鼓励使用这些动物成分。迄今为止，InVitria已开发并商业化了八种重组蛋白和细胞培养基补充剂。InVitria的产品开发团队有一个积极的计划，可以根据客户需求扩展该产品线。