品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
ProductDescription
VX-680(Tozasertib)isasmallmoleculeAurorakinaseinhibitor(Aurora-A~0.6nM,Aurora-B~18nM,Aurora-C~4.6nM).VX-680inhibitscellcycleprogression,inducesapoptosisandblockstumorgrowthinvarietiesofinvivoxenograftmodels,includingleukemia,colonandpancreatictumors.
Technicalinformation:
| ChemicalFormula: | C23H28N8OS | |
| CAS#: | 639089-54-6 | |
| MolecularWeight: | 464.59 | |
| Purity: | >98% | |
| Appearance: | Lightyellowsolid | |
| ChemicalName: | N-(4-((4-((5-methyl-1H-pyrazol-3-yl)amino)-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl)thio)phenyl)cyclopropanecarboxamide | |
| Solubility: | Upto100mMinDMSO |
ShippingCondition:Theproductisshippedinaglassvialatambienttemperature.
Storage:Forlongershelflife,storesolidpowderat4oCdesiccated,orstoreDMSOsolutionat-20oC.
Reference:
| 1. | ElizabethAHarrington,etal.VX-680,apotentandselectivesmall-moleculeinhibitoroftheAurorakinases,suppressestumorgrowthinvivo.NatureMedicine2004;10,262–267. |
| 2. | MarumotoT,ZhangD,SayaH.Aurora-A-aguardianofpoles.NatRevCancer.2005;5(1):42-50. |
Cellagen的FlexiWash FW400自动膜/凝胶洗涤站设计用于自动Western blot膜洗涤和孵育过程。将蛋白质转移到膜上后，将膜加载到FlexiWash上以进行自动封闭，孵育和洗涤循环。用户只需要准备所需的试剂，启动印迹程序，然后让FW400进行其余操作即可。凭借独特的液体处理设计，FW400同时支持四个清洗/孵育过程，每个过程均可独立编程，并针对特定应用实现全自动。FW400也可用于蛋白质或DNA凝胶染色和脱色，或涉及重复液体处理和孵育周期的任何其他应用。
