Stemrd/噻唑维文/5毫克/THIA-005

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¥3780.00
货号:THIA-005
浏览量:127
品牌:Stemrd
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商品描述
SourceM.W.311.36CAS No.1226056-71-8
Structural InfoThiazovivin
FormulationPowder
ReconstitutionBefore reconstitution, we recommend a brief spin todrive down any material dislodged from the bottom of the tube. The compound is soluble in DMSO.
StabilityThe powder is stable for at least 1 year if stored at-20 °C.The dissolved compound isstable for at least 1 month at 4 °C, but should be stored in aliquots at-20 °C for longer term. Protectfrom light.
PurityGreater than 99% as determined by LC/MS analysis.LC/MS and/or NMR data available upon request.
Biological ActivityTested active for culturing human iPS cells in serum-free medium on Matrigel coated plates.
Country of OriginUSA

Thiazovivin,N-benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide, is a selectiveinhibitor of Rho-associated kinase (ROCK). It protects human ES cells from death in the absence of ECM byregulating E-cadherin mediated cell-cell interaction.Thiazovivin, in combination with inhibitorsof the TGF-beta receptor and the MEK kinases, improves reprogramming efficiencydramatically.Ref: Lin, T., et al. (2009) Achemical platform for improved induction of human iPSCs. Nature Methods. 6(11):805.

Product Sheet
Stemrd的WNT-5a属于激活“非规范”途径的WNT蛋白类别。小鼠WNT-5a的预测大小是一种包含356个氨基酸残基的单体蛋白。由于糖基化作用,在非还原条件下,通过SDS-PAGE分析,它以〜45 kDa的表观分子量迁移。StemRD的产品是从小鼠细胞系表达而来,并通过不同于公开方法的专有工艺进行纯化。