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4000-520-616 / 18915418616
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商品描述
BIOLOGICAL INFORMATION
DescriptionThis peptide is a 1 to 20 amino acid fragment of the interphotoreceptor retinoid binding protein (IRBP). IRBP is a 140-kDa glycolipoprotein residing in the interphotoreceptor matrix between the neural retina and the retinal pigment epithelium. Human IRBP peptide 1-20 contains a major epitope for the H-2b haplotype. Immunization with IRBP (1 – 20) induces T-cell–mediated experimental autoimmune uveoretinitis (EAU) disease. The pathology of disease induced by the peptide, or by adoptive transfer of cells specific to the peptide, is similar to that induced by the whole IRBP protein.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10787
CAS No.N/A
NameIRBP (1-20), human
Chemical NameIRBP-(1-20),-human
Purity≥98%
SynonymsN/A
FormulaC101H164N24O28S1
Molecular Weight2194.6
One Letter CodeGPTHLFQPSLVLDMAKVLLD
Three Letter CodeGly-Pro-Thr-His-Leu-Phe-Gln-Pro-Ser-Leu-Val-Leu-Asp-Met-Ala-Lys-Val-Leu-Leu-Asp
SMILESN/A
InChI KeyN/A
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
Stability≥ 2 years
REFERENCES & CITATIONS
1.Avichezer, D. et al. Invest. Ophthalmol. Visual Sci. 41, 127 (2000)
2.Lee DJ., et al. Both MC5r and A2Ar Are Required for Protective Regulatory Immunity in the Spleen of Post–Experimental Autoimmune Uveitis in Mice. J Immunol. 2013 Qct;191(8):4103-11.
3.Darren J. Lee and Andrew W. Taylor.., et al. Following Eau Recovery There Is An Associated Mc5R-Dependent Apc Induction Of Regulatory Immunity In The Spleen. Invest Ophthalmol Vis Sci. 2011 Nov;52(12):8862-7
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
