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商品描述
BIOLOGICAL INFORMATION
DescriptionHexarelin (HEX) is a peptide GH secretagogue with a potent ability to stimulate GH secretion and recently reported cardioprotective actions. However, hexarelin (HEX) effects in the brain are largely unknown, and the aim of the present study was to examine the potential protective effect of hexarelin (HEX) on the central nervous system after injury, as well as on caspase-3, Akt, and extracellular signal-regulated protein kinase (ERK) signaling cascades in a rat model of neonatal hypoxia-ischemia.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10600
CAS No.140703-51-1
NameHexarelin
Chemical NameHexarelin
Purity≥98%
SynonymsExamorelin
FormulaC47H58N12O6
Molecular Weight887
One Letter CodeHWAWFK-NH2
Three Letter CodeHIS-D-2-ME-TRP-ALA-TRP-d-PHE-LYS-NH2
SMILESCC1=C(C2=CC=CC=C2N1)CC(C(=O)NC(C)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CC5=CC=CC=C5)C(=O)NC(CCCCN)C(=O)N)NC(=O)C(CC6=CN=CN6)N
InChI KeyRVWNMGKSNGWLOL-GIIHNPQRSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingIce Pack
Stability≥ 2 years
REFERENCES & CITATIONS
1.Guerlavais Vet al. New active series of growth hormone secretagogues. J Med Chem 46:1191-203 (2003). Read more (PubMed: 12646029)
2.Orkin RDet al. Rapid desensitisation of the GH secretagogue (ghrelin) receptor to hexarelin in vitro. J Endocrinol Invest 26:743-7 (2003). Read more (PubMed: 14669829)
3.Rossoni Get al. Protectant activity of hexarelin or growth hormone against postischemic ventricular dysfunction in hearts from aged rats. J Cardiovasc Pharmacol 32:260-5 (1998). Read more (PubMed: 9700988)
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
