Description

Coronaviruses are a large family of viruses that are common in people and many different species of animals including camels, cattle, cats, and bats.In December 2019, a cluster of patients with a novel coronavirus was identified in Wuhan, China. The virus named SARS-CoV-2 can cause the disease named coronavirus disease 2019 (COVID-2019) [WHO, 2 March 2020].During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as an optimal diagnostic marker. Two types of antibodies against this virus (IgM and IgG) are produced and secreted into the circulation by the immune system. COVID-19 ELISA IgG DIATHEVA kit is a Immunoenzymic essay (ELISA) for the determination of IgG antibodies to the COVID-19 coronavirus Nucleocapsid (N). The kit is equipped with positive and negative synthetic controls as well as a control on the blank value.