This standard is prepared from sterile-filtered human male AB plasma (USA origin), obtained from a large number of qualified (healthy, non-medicated) adult blood donors. The nephelometric determination of the concentration of each of the four subclasses was carried out on a Beckman Coulter IMMAGE® Immunochemistry System, using the Sanquin Kit for quantitative determination of human IgG subclasses in serum and plasma. Maximum allowable imprecision is 15%.The standard used was from Siemens which is calibrated against the ERM-DA470 (CRM-470) standard.Each donor is tested for and found non-reactive for Hepatitis B & C and non-reactive for Human Immunodeficiency Virus (HIV) antibody by ELISA. Nevertheless, products of human origin should be considered potentially infectious and handled accordingly.Human standard serum NOR-01 is intended for use as a calibrator to prepare standard curves in quantitative determinations of human IgG subclasses.

Liquid whole serum. No preservative added.