Cell Technology/Fluoro BChE/100/FLBCHE100

价格
面议
货号:FLBCHE100
浏览量:127
品牌:Cell Technology
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商品描述
  • Description
  • Additional information

Introduction

Butyrylcholinesterase (BChE) belongs to the same structural class of proteins as acetylcholinesterase (AChE). The 440kDa tetrameric glycoprotein is predominantly found in blood, kidneys, intestine, liver, lung, heart and the central nervous system. BChE preferentially acts on butyrylcholine, but also hydrolyzes acetylcholine. Alzheimer’s disease appears to be associated with decreased acetylcholinesterase activity and an increase in Butyrylcholinesterase activity. BChE activity, therefore, has potential applications as a biomarker for progression or as a target for future therapies.

Key Benefits

  • Measure BChE activity as fluorescent readout; endpoint or kinetically.
  • Run serum, plasma, CSF or cell/tissue lysates as samples.
  • Sensitive - measure <0.02mU/ml of BChE activity.

Additional information

Kit Size

100

Cell Technology的Apo Active 3PE对活性人和鼠半胱天冬酶3具有高度特异性。其他测定需要利用基于肽的(DEVD)试剂,这些试剂倾向于与半胱天冬酶7和其他半胱天冬酶交叉反应。应用 –流式细胞仪,荧光显微镜或荧光酶标仪。产生定量和定性结果。发出强烈的积极信号。可以与其他抗体或染色剂一起使用。无需进行细胞裂解液或蛋白质印迹分析。单元可以固定,以后再分析。适用于人类,小鼠和大鼠细胞系。