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商品描述
Product information "(±)14(15)-EpETE"
EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators. Cytochrome P450 (CYP450) metabolism of polyunsaturated fatty acids, produces epoxides such as (±)14(15)-EpETrE (Cay-50651) which are prime candidates for the actual active mediator. However, the CYP450 metabolites of eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310) have been little studied relative to arachidonate epoxygenase metabolites. (±)14(15)-EpETE is the omega-3 homolog of 14(15)-EpETrE, derived via epoxidation of the 14,15-double bond of EPA. The EDHF activity of (±)14(15)-EpETE has not yet been determined.
| Keywords: | (±)14,15 EEQ, (±)14,15-epoxy Eicosatetraenoic Acid, (±)14,15-epoxy-5Z,8Z,11Z,17Z-eicosatetraenoic acid |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 10173-25 |
Properties
| Application: | Bioactive lipid assays |
| MW: | 318.5 D |
| Formula: | C20H30O3 |
| Purity: | >90% |
| Format: | Solution |
Database Information
| CAS : | 131339-24-7| Find alternatives |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |  |
| H Phrases: | H225 |
| P Phrases: | P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, P501 |
Caution Our products are for laboratory research use only: Not for administration to humans!
