Availability: In StockBiological Description:Bisoprolol is a selective type β1 adrenergic receptor blocker.Target: Adrenergic ReceptorApproved: July 31, 1992Bisoprolol, on beta 1-adrenoceptor peptide induced autoimmune myocardial damage. In the animal model of autoimmune cardiomyopathy induced by active immunization of rabbits with beta 1-adrenoceptor peptide, bisoprolol was given at a dose of 3 mg/day throughout the study period. Our results showed high titer of anti-beta 1-adrenoceptor antibody in the immunized group throughout the study but not in the group receiving only bisoprolol [1]. Bisoprolol administration resulted in a significant reduction in HR reaching 60.3 +/- 1.4 bpm at VT of 500 mL (compared to 70.5 +/- 1.8 bpm with placebo, P < 0.001).="" changes="" in="" hp="" were="" also="" significant="" with="" an="" increase="" in="" hp="" reaching="" 1004.5="" +/-="" 22.2="" msec="" at="" this="" controlled="" vt="" (compared="" to="" 860.3="" +/-="" 21.5="" msec="" with="" placebo,="" p="">< 0.001)="">Toxicity: Oral, mouse: LD50 = 100 mg/kg; Skin, rabbit: LD50 = 200 mg/kg; Skin, rat: LD50 = 500 mg/kg. Symptoms of overdo...Purity: >98%Molecular formula: C₄₀H₆₆N₂O₁₂Molecular Weight: 766.96Storage Instructions: Two years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSOReferences: for more information, please visit images/AffixScientific/ Affix Scientific毒素和天然物质乙酰肾上腺素（14-）CAS号： 71609-79-5化学名称：71609-79-5> 99％20毫克100毫克$ 500$ 1500乌头碱CAS号： 302-27-2化学名称：302-27-2> 98％100毫克500毫克$ 500$ 1600乌头酸CAS号： 38839-95-1化学名称：38839-95-1> 98％20毫克100毫克$ 500$ 1400阿科林CAS号： 110225-59-7化学名称：110225-59-7> 98％20毫克100毫克$ 500$ 1500茉莉花CAS号： 509-17-1化学名称：509-17-1> 98％20毫克100毫克$ 500$ 1200阿苯达唑CAS号： 54965-21-8化学名称：54965-21-8> 98％200毫克1000毫克$ 500$ 1300别氯CAS号： 141489-39-6化学名称：141489-39-6> 80％100毫克500毫克$ 500$ 1700