粘贴Scientific/KRN 633/1g/286370-15-8

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货号:286370-15-8
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Cat No.: 286370-15-8
Biological Description:KRN633 is a potent and selective VEGFR inhibitor. which inhibits tyrosine phosphorylation of VEGFR-2 (IC50 = 1.16 nmol/L) in human umbilical vein endothelial cells. Selectivity profiling with recombinant tyrosine kinases showed that KRN633 is highly selective for VEGFR-1, -2, and -3. KRN633 inhibits tumor growth in several in vivo tumor xenograft models with diverse tissue origins, including lung, colon, and prostate, in athymic mice and rats. KRN633 also causes the regression of some well-established tumors and those that had regrown after the cessation of treatment. KRN633 was well tolerated and had no significant effects on body weight or the general health of the animals. KRN633 might be useful in the treatment of solid tumors and other diseases that depend on pathologic angiogenesis.Purity: >98.00%Molecular formula: C20H21ClN4O4 Molecular Weight: 446.90Storage Instructions: Two years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSOReferences: for more information, please visit images/AffixScientific/ Affix Scientific毒素和天然物质乙酰肾上腺素(14-)CAS号: 71609-79-5化学名称:71609-79-5> 99%20毫克100毫克$ 500$ 1500乌头碱CAS号: 302-27-2化学名称:302-27-2> 98%100毫克500毫克$ 500$ 1600乌头酸CAS号: 38839-95-1化学名称:38839-95-1> 98%20毫克100毫克$ 500$ 1400阿科林CAS号: 110225-59-7化学名称:110225-59-7> 98%20毫克100毫克$ 500$ 1500茉莉花CAS号: 509-17-1化学名称:509-17-1> 98%20毫克100毫克$ 500$ 1200阿苯达唑CAS号: 54965-21-8化学名称:54965-21-8> 98%200毫克1000毫克$ 500$ 1300别氯CAS号: 141489-39-6化学名称:141489-39-6> 80%100毫克500毫克$ 500$ 1700