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abbomax/血管加压素V1b受体/100ug/500-10214

价格
面议
货号:500-10214
浏览量:103
品牌:abbomax
服务
全国联保
正品保证
正规发票
签订合同
商品描述
Vasopressin V1b Receptor
Arginine vasopressin receptor 1B (VR1b); VPR; AVPR
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Product Preparation
A synthetic peptide corresponding to the extracellular domain of V1b vasopressin receptor.This sequence is identical to human, mouse and rat.
Background
The vasopressin r V1B eceptorV1bR is a member of the Vasopressin/Oxytocin G-protein coupled receptors family . The V1B receptor is expressed specifically in pituitary corticotropes and mediates the stimulatory effect of vasopressin on ACTH release. Vasopressin V1B receptor expression has been documented in the pituitary, pituitary tumors, pheochromocytoma, breast cancer, and small-cell lung carcinomas.
PURIFICATION
The Rabbit IgG is purified by Epitope Affinity Purification
SPECIFICITY
This antibody recognizes V1bR protein.It cross-reacts to human, mouse and rat. Others are not tested.
FORMULATION
This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
STORAGE
The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity.Avoid repeated freezing-thawing cycles.
Gene ID
553
Applications/Suggested Working Dilutions
Western Blot
0.1-1 µg/ml
ELISA
0.01-0.1 µg/ml
Immunoprecipitation
2-5µg/ml
IHC
1-5µg/ml
Flow cytometry
Not tested
abbomax的14-3-3蛋白是一类小而广泛表达的高度保守的胞质蛋白。14-3-3蛋白与包括Raf,PKC,Bad,Cbl和c-Bcr在内的信号转导,细胞周期调控和细胞凋亡的各种分子结合并影响其活动。14-3-3与靶蛋白之间的相互作用受14-3-3与靶蛋白的磷酸化状态强烈影响。14.3.3β在脑组织中高度表达。这对于细胞转化和有丝分裂信号传导至关重要。