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商品描述
Claudin 7
CLDN7; CEPTRL2, CPETRL2, Hs.84359, claudin-7
Download Product PDFProduct Preparation
peptide from C-terminus of human claudin 7 protein. This sequence is identical to human, rat, mouse and bovine.
Background
The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four trans-membrane domains and two extracellular loops, make up tight junction strands. Claudin 7 (CLDN7) has two isoforms, a full-length form with 211 aa residues and a C-terminal truncated form with 158 aa residues. This protein is localized in the intercellular junctions of the epithelial cells of the proximal tubules of the nephrons in mammalian kidney. It is expressed in normal human and mouse epithelia.
PURIFICATION The Rabbit IgG is purified by Epitope Affinity Purification | SPECIFICITY This antibody reacts human, mouse and rat.The other species are not tested. |
FORMULATION This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer. | STORAGE The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity.Avoid repeated freezing-thawing cycles. |
Gene ID
1366
Applications/Suggested Working Dilutions
Western Blot 0.1-1 µg/ml | ELISA 0.01-0.1 µg/ml | Immunoprecipitation 2-5µg/ml | IHC 0.5-2 µg/ml | Flow cytometry Not tested |
