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蚂蚁淘在线 / 品牌中心 / Immunoway / 免疫法/TORC1/CRTC1（磷酸化Ser151）兔pAb/20ug 50ug 100ug/YP1534

免疫法/TORC1/CRTC1（磷酸化Ser151）兔pAb/20ug 50ug 100ug/YP1534

价格
￥1700.00
货号：YP1534
浏览量：127
品牌：Immunoway
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商品描述

TORC1/CRTC1 (phospho-Ser151) rabbit pAb

  • Catalog No.：YP1534
  • Applications：WB
  • Reactivity：Human
  • Data Sheet
  • MSDS
  • Support
  • Description
  • References ( 0 )
  • Protocol
    • Gene Name：
    • CRTC1 KIAA0616 MECT1 TORC1 WAMTP1
    • Protein Name：
    • TORC1/CRTC1 (Ser151)
    • Human Gene Id：
    • 23373
    • Human Swiss Prot No：
    • Q6UUV9
    • Mouse Gene Id：
    • 382056
    • Mouse Swiss Prot No：
    • Q68ED7
    • Rat Gene Id：
    • 684527
    • Rat Swiss Prot No：
    • Q157S1
    • Immunogen：
    • Synthesized phosho peptide around human TORC1 and CRTC1 (Ser151)
    • Specificity：
    • This antibody detects endogenous levels ofHuman TORC1 or CRTC1 (phospho-Ser151)
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Rabbit
    • Dilution：
    • WB 1:1000-2000
    • Purification：
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -20°C/1 year
    • Other Name：
    • CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1)
    • Observed Band(KD)：
    • 70
    • Function：
    • disease:A chromosomal aberration involving CRTC1 is found in mucoepidermoid carcinomas, benign Warthin tumors and clear cell hidradenomas. Translocation t(11;19)(q21;p13) with MAML2. The fusion protein consists of the N-terminus of CRTC1 joined to the C-terminus of MAML2. The reciprocal fusion protein consisting of the N-terminus of MAML2 joined to the C-terminus of CRTC1 has been detected in a small number of mucoepidermoid carcinomas.,function:Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 "Ser-133" phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator
    • Subcellular Location：
    • nucleus,nucleoplasm,cytoplasm,plasma membrane,dendrite,neuronal cell body,synapse,
    • Expression：
    • Brain,Carcinoma,Colon,Embryo,Eye,
    • June 19-2018
    • WESTERN IMMUNOBLOTTING PROTOCOL
    • June 19-2018
    • IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
    • June 19-2018
    • IMMUNOFLUORESCENCE PROTOCOL
    • June 19-2018
    • FLOW CYTOMEYRT PROTOCOL
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
    • July 13-2018
    • CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
    • July 13-2018
    • Antibody-FAQs
    Immunoway二抗可与酶，生物素或荧光团偶联，可用于多种基于抗体的应用，包括Western Blot，ImmunoHistoChemistry，ImmunoFluorescence，流式细胞术和ELISA。我们为您的每种应用提供来自山羊，兔和驴的高质量二抗。也可以使用血清吸附的二抗，建议将其用于富含免疫球蛋白的样品。