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蚂蚁淘在线 / 品牌中心 / Immunoway / 免疫法/TTF-1（磷酸化-Ser327）兔pAb/20ug 50ug 100ug/YP1537

免疫法/TTF-1（磷酸化-Ser327）兔pAb/20ug 50ug 100ug/YP1537

价格
￥1700.00
货号：YP1537
浏览量：127
品牌：Immunoway
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商品描述

TTF-1 (phospho-Ser327) rabbit pAb

  • Catalog No.：YP1537
  • Applications：WB
  • Reactivity：Human
  • Data Sheet
  • MSDS
  • Support
  • Description
  • References ( 0 )
  • Protocol
    • Gene Name：
    • NKX2-1 NKX2A TITF1 TTF1
    • Protein Name：
    • TTF-1 (Ser327)
    • Human Gene Id：
    • 7080
    • Human Swiss Prot No：
    • P43699
    • Mouse Gene Id：
    • 21869
    • Mouse Swiss Prot No：
    • P50220
    • Rat Swiss Prot No：
    • P23441
    • Immunogen：
    • Synthesized phosho peptide around human TTF-1 (Ser327)
    • Specificity：
    • This antibody detects endogenous levels ofHuman TTF-1 (phospho-Ser327)
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Rabbit
    • Dilution：
    • WB 1:1000-2000
    • Purification：
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -20°C/1 year
    • Other Name：
    • Homeobox protein Nkx-2.1 (Homeobox protein NK-2 homolog A) (Thyroid nuclear factor 1) (Thyroid transcription factor 1) (TTF-1)
    • Observed Band(KD)：
    • 38
    • Background：
    • NK2 homeobox 1(NKX2-1)Homo sapiensThis gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014],
    • Function：
    • disease:Defects in NKX2-1 are the cause of benign hereditary chorea (BHC) [MIM:118700]; also known as hereditary chorea without dementia. BHC is an autosomal dominant movement disorder. The early onset of symptoms (usully before the age of 5) and the observation that in some BHC families the symptoms tend to decrease in adulthood suggests that the disorder results from a developmental disturbance of the brain. BHC is non-progressive and patients have normal or slightly below normal intelligence. There is considerable inter- and intrafamilial variability, including dysarthria, axial distonia and gait disturbances.,disease:Defects in NKX2-1 are the cause of choreoathetosis, hypothyroidism, and neonatal respiratory distress (CHNRD) [MIM:610978]. This syndrome include neurological, thyroid, and respiratory problems.,function:Transcription factor that binds and activates the promoter of thyro
    • Subcellular Location：
    • nucleus,nucleoplasm,transcription factor complex,
    • Expression：
    • Lung,Thyroid,
    • June 19-2018
    • WESTERN IMMUNOBLOTTING PROTOCOL
    • June 19-2018
    • IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
    • June 19-2018
    • IMMUNOFLUORESCENCE PROTOCOL
    • June 19-2018
    • FLOW CYTOMEYRT PROTOCOL
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
    • July 13-2018
    • CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
    • July 13-2018
    • Antibody-FAQs
    Immunoway二抗可与酶，生物素或荧光团偶联，可用于多种基于抗体的应用，包括Western Blot，ImmunoHistoChemistry，ImmunoFluorescence，流式细胞术和ELISA。我们为您的每种应用提供来自山羊，兔和驴的高质量二抗。也可以使用血清吸附的二抗，建议将其用于富含免疫球蛋白的样品。