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蚂蚁淘在线 / 品牌中心 / Immunoway / Immunoway/β-Arrestin 1 (phospho-Ser412) rabbit pAb/20ug 50ug 100ug/YP1557

Immunoway/β-Arrestin 1 (phospho-Ser412) rabbit pAb/20ug 50ug 100ug/YP1557

价格
￥1700.00
货号：YP1557
浏览量：127
品牌：Immunoway
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商品描述

β-Arrestin 1 (phospho-Ser412) rabbit pAb

  • Catalog No.：YP1557
  • Applications：WB
  • Reactivity：Human,Mouse,Rat
  • Data Sheet
  • MSDS
  • Support
  • Description
  • References ( 0 )
  • Protocol
    • Gene Name：
    • ARRB1 ARR1
    • Protein Name：
    • β-Arrestin 1 (Ser412)
    • Human Gene Id：
    • 408
    • Human Swiss Prot No：
    • P49407
    • Mouse Gene Id：
    • 109689
    • Mouse Swiss Prot No：
    • Q8BWG8
    • Rat Gene Id：
    • 25387
    • Rat Swiss Prot No：
    • P29066
    • Immunogen：
    • Synthesized phosho peptide around human β-Arrestin 1 (Ser412)
    • Specificity：
    • This antibody detects endogenous levels ofHuman Mouse Rat β-Arrestin 1 (phospho-Ser412)
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Rabbit
    • Dilution：
    • WB 1:1000-2000
    • Purification：
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -20°C/1 year
    • Other Name：
    • Beta-arrestin-1 (Arrestin beta-1)
    • Observed Band(KD)：
    • 47
    • Background：
    • arrestin beta 1(ARRB1)Homo sapiensMembers of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011],
    • Function：
    • function:Regulates beta-adrenergic receptor function. Beta-arrestins seem to bind phosphorylated beta-adrenergic receptors, thereby causing a significant impairment of their capacity to activate G(S) proteins.,online information:Arrestin entry,similarity:Belongs to the arrestin family.,
    • Subcellular Location：
    • Golgi membrane,chromatin,nucleus,nucleoplasm,cytoplasm,lysosomal membrane,cytosol,heterotrimeric G-protein complex,plasma membrane,clathrin-coated pit,postsynaptic density,basolateral plasma membrane,cytoplasmic vesicle membr
    • Expression：
    • Brain,Peripheral blood,Uterus,
    • June 19-2018
    • WESTERN IMMUNOBLOTTING PROTOCOL
    • June 19-2018
    • IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
    • June 19-2018
    • IMMUNOFLUORESCENCE PROTOCOL
    • June 19-2018
    • FLOW CYTOMEYRT PROTOCOL
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
    • July 13-2018
    • CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
    • July 13-2018
    • CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN
    • July 13-2018
    • Antibody-FAQs
    Immunoway二抗可与酶，生物素或荧光团偶联，可用于多种基于抗体的应用，包括Western Blot，ImmunoHistoChemistry，ImmunoFluorescence，流式细胞术和ELISA。我们为您的每种应用提供来自山羊，兔和驴的高质量二抗。也可以使用血清吸附的二抗，建议将其用于富含免疫球蛋白的样品。