CatalogNo.: T-1900 Description: TheS1PassayservicesusestheS1PELISAkit(K-1900)toquantifyLPAinBIOLOGicalsamples(96-wellformat).Sphingosine1Phosphate(S1P)isakeycomponentofthesphingolipidsignalingcascade.S1Pinitiatesaproliferative,pro-angiogenic,andanti-apoptoticsequenceofeventscontributingtocancerprogression.RecentresearchhassuggestedthatS1PisapotenttumOrigenicgrowthfactorthatislikelyreleasedfromtumorcellsandthatS1PmaybeanovelbioMarkerforearlystagecancerdetection.Sphingosinekinasehasalsobeenshowntobeup-regulatedinavarietyofcancertypes(S1Pisproducedviatheactivityofsphingosinekinasephosphorylatingsphingosine).TheEchelonS1PAssayisasensitiveandrobustmethodforthequantificationofS1Pinbiologicalsamples.
Pleaserefertothetechnicaldatasheetforsampleconsiderationsandshippinginformation.ToplaceanorderpleasecontactEchelonat801.588.0455. Disclaimer: TheS1PAssayServicewasco-developedusingaproprietarymonoclonalantibodyfromLpathInc.(SanDiego,CA).Lpath,Inc.hasanumberofpatentapplicationspendingorissuedcoveringmaterial(s)incorporatedintothisassay.Theassay’ssolepermitteduseisfornon-clinicalresearchtomeasureS1Pinbiologicalsamples.Anyotheruse,includingdrugdiscovery,requiresalicensefromLpath.(www.lpath.com).

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