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![]() | CatalogNo.: K-6000 Description: Echelon’sHyaluronidaseActivityELISAisaquantitativeimmunoassaydesignedforinvitromeasurementofhyaluronidaseactivityinBIOLOGicalsamples. | ||
HyaluronidasesareagroupofenzymesthatdegradeHyaluronan(HA),alinearpolysaccharidecomprisedofarepeatingdisaccharideofN-acetylglucosamineandD-glucuronicacid.HAisinvolvedinmanybiologicalprocessesincludingstructuralsupport,cellmigrationandtissueturnover.CirculatingHAlevelshavealsobeenshowntocorrelateinseveraldisorderssuchasliverdiseaseandcertaintypesofcancer.HyaluronidaseshavebecomeanimportantareaofstudyduetotheirregulatoryfunctioninHAmetabolismandtheirroleinphysiologicalprocessessuchasfertilizationandwoundhealing.ElevatedexpressionlevelsofthegeneencodingHyaluronidase1havebeenfoundinatypicalductalhyperplastictissues,suggestingthepossibilitythatitmaybeaviablebioMarkerforidentifyingpremalignantlesionsthatcandevelopintobreastcancer.Researchhasalsoshownthathyaluronidasesareinvolvedinseveralpathologicalprocessessuchasbacterialpathogenesis,thespreADIngoftoxins/venomsandcancerprogression,makinghyaluronidasesapotentialpharmacologicaltarget. StoragePart1at-20°CandPart2at4°CRelatedProducts:HAELISA(K-1200),HASandwichELISA(K-4800),CollagenIVELISAKit(K-1700). ProductKeywords:Hyaluronan,Hyaluronate,LiverCirrhosis,RheumatoidArthritis,Osteoarthritis,LiverFibrosis | |||



