CatalogNo.: K-5300 Description: Echelon’sHeparinELISAisaquantitativeimmunoassaydesignedforinvitromeasurementofheparininpurified/syntheticsamples.
ProductBackground:Heparinisahighlysulfatedglycosaminoglycanranginginsizefrom6to20kDa.Heparinispresentedinmastcell,liverandlungs.Althoughitsfunctionisunknown,itiswidelyusedasananticoagulanttopreventbloodclottinginvivoandinvitro.Forexample,heparinisusedaspreventativetreatmentfordeepveinthrombosisandpulmonaryembolism.Oversulfatedchondroitinsulfatecontaminationinrawheparinstocksusedforinjectableheparinmanufacturingwasdiscoveredin2008andresultedinamajorrecallofrelatedmedicalproducts.AccordingtotheFDA,itisbelievedatleast11deathswereassociatedwiththecontaminatedheparin-containingdevicesworldwide.Therefore,ensuringpurityofrawhepariniscriticalinmedicalheparinmanufacturing. Storage 4°C References Cai,S.etal."ASelectiveProteinSensorforHeparinDetection."AnalBiochem.326(1),33-41(2004).

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