CatalogNo.: P-9C2 Description: HistoneH1hassuccessfullydeliveredthefollowingphosphoinositidesintocells:PtdIns(4,5)P2,PtdIns(3,4)P2,PtdIns(3,5)P2,PtdIns(3,4,5)P3,andtheirfluorescentanalogs.ThiscarriercanalsobefoundintheseShuttlePIPkits:P-9039,P-9034,P-9045,&P-9035.
Toprovideourcustomerswithadditionaloptionsindesigningtheirowncell-deliveryapplications,Echelonoffersfluorescentandnon-fluorescentcarriersasstandaloneproductsoutsideourShuttlePIPsTMkits.Customerscanusethemosteffectivecarrierfortheirsystemalongwiththeindividualfluorescentornon-fluorescentphosphoinositidesoftheirchoice. Providedas2x50nmoles Storage 2-8°C,Donotfreezethawmultipletimes.Note:phosphatebuffersarenotrecommendedandmayaltercomplexformationwithphosphoinositides.WedonotrecommendstoringcarriersandPIPstogetherascomplexes. FeaturedinReferences 1)Maffucci,T.,A.Brancaccio,etal.(2003)."Insulininducesphosphatidylinositol-3-phosphateformationthroughTC10activation."EmboJ22(16):4178-89. 2)Soughayer,J.S.,Y.Wang,etal.(2004)."CharacterizationofTAT-mediatedtransportofdetachablekinasesubstrates."Biochemistry43(26):8528-40. 3)Im,E.,S.H.Rhee,etal.(2010)."Corticotropin-releasinghormonefamilyofpeptidesregulatesintestinalangiogenesis."Gastroenterology138(7):2457-67

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