PI(3)P diC16 (Phosphatidylinositol 3-phosphate diC16) is a synthetic, purified dipalmitoyl PI(3)P.

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3-phosphate is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4.

Product Keywords: Dipalmitoyl Phosphatidylinositol 3-phosphate, PtdIns(3)P C16, PI(3)P C16, or PI3P

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Publications

1) Sbrissa, D., O. C. Ikonomov, et al. (2000). “PIKfyve lipid kinase is a protein kinase: downregulation of 5′- phosphoinositide product formation by autophosphorylation [In Process Citation].” Biochemistry 39(51): 15980-9.2) Kutateladze, T. G., D. G. Capelluto, et al. (2004). “Multivalent mechanism of membrane insertion by the FYVE domain.” J Biol Chem 279(4): 3050-7.3) Wollert, T., C. Wunder, et al. (2009). “Membrane scission by the ESCRT-III complex.” Nature 458(7235): 172-7.

Categories	Lipids
Filter	diC16, Phosphoinositides, PI(3)P
CAS Number	165689-81-6
Molecular Formula	C41H77Na3O16P2
Molecular Weight (g/mol)	956.96
Purity	>95%
Storage	-20 °C or below

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