XY-14 is a competitive inhibitor of Lipid Phosphate Phosphatase 1 (LPP1) which is the major enzyme responsible for degrading lysophosphatidic acid (LPA) in platelets. XY-14 (10 μM) inhibits LPP1 in human pulmonary artery endothelial cells, preventing the dephosphorylation of sphingosine 1-phosphate (S1P) to sphingosine. XY-14 is also reported to inhibit LPP2 & LPP3 ⁽¹⁾.

Categories	Biochemical Reagents
Filter	Inhibitor, Lysophosphatidic Acid, Phosphatidic Acid
CAS Number	478529-66-7
Molecular Formula	C40H71F2Na2O7P
Molecular Weight (g/mol)	778.94
Purity	95%
Storage	-20 °C or below

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