DescriptionSequence(One-Letter Code)

Product Name	BombesinPyr - QRLGNQWAVGHLM - NH2
Size	1 mg
Catalog #	AS-20665
US$	$40
Purity	% Peak Area By HPLC ≥ 95%
This 14-amino-acid bombesin peptide is homologous to the C terminus of Gastrin-Releasing Protein (GRP). It binds with high affinity to the GRP receptor, a member of the G-protein-coupled receptor family.
Detailed Information	Datasheet Material Safety Data Sheets (MSDS)
Storage	-20°C
References	Ref: Dietrich, JB. Cell. Mol. Biol. 40, 731 (1994).
Molecular Weight	1620.9
Pyr-QRLGNQWAVGHLM-NH2
Sequence(Three-Letter Code)	Pyr - Gln - Arg - Leu - Gly - Asn - Gln - Trp - Ala - Val - Gly - His - Leu - Met - NH2
Product Citations	Shrivastava, A. et al. (2014). A high-affinity near-infrared fluorescent probe to target bombesin receptors. Mol Imaging Biol 16, 661.Shrivastava, A. et al. (2013). Heterobivalent dual-target probe for targeting GRP and Y1 receptors on tumor cells. Bioorg Med Chem Lett 23, 687. doi: 10.1016/j.bmcl.2012.11.110.O"Donoghue, A. et al. (2008). Inhibition of a secreted glutamic peptidase prevents growth of the fungus Talaromyces emersonii. J Biol Chem 283, 29186. doi:10.1074/jbc.M802366200.Bogunovic, Milena. et al. (2007). Enteroendocrine cells express functional Toll-like receptors. Am J Phisiol Gastrointest Liver Phisiol 292, G1770. doi: 10.1152/ajpgi.00249.2006.

Anaspec在过去的二十年中，荧光检测生理学和神经学信号受到了极大的关注。使用分子荧光或发光来感测生理和神经信号具有若干优点。其中包括高灵敏度（低至单个分子），开-关切换性，活细胞通信的可行性，具有亚微米可视化的亚纳米空间分辨率和亚毫秒级时间分辨率。光诱导电子转移（PET）和电子能量转移（EET）主要用于将离散的和化学计量的识别事件转换为荧光信号。基于PET效应，开发了许多荧光生理指示剂（如下所述）。AnaSpec提供高质量和具有竞争力的价格的多种生理和神经指标（例如Fura-2，Indo-1和Rhod-2），用于各种生物学应用。AnaSpec努力提供可在任何地方使用的最高纯度的指标。通过HPLC分析，我们的UltraPure级AM荧光指示剂酯的纯度通常至少为95％，尽管纯度通常超过98％。此外，我们还为您提供许多Ca2 +指示剂的AM酯的定制包装服务，以最小的费用为您提供便利，并降低了存储期间变质的风险。