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蚂蚁淘在线 / 品牌中心 / Abcam / Abcam/Y-27632 dihydrochloride, Rho kinase inhibitor (ab120129)/1/ab120129

Abcam/Y-27632 dihydrochloride, Rho kinase inhibitor (ab120129)/1/ab120129

价格
面议
货号：ab120129
浏览量：127
品牌：Abcam
服务
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商品描述

Overview

  • Product name

    Y-27632 dihydrochloride, Rho kinase inhibitor

  • Description

    Selective Rho kinase inhibitor

  • Biological description

    Y-27632 is a research tool with a wide variety of biological effects, mainly used in the field of stem cell research for maintenance and differentiation.Commonly used as 3D growth matrix component; also a component of brain organoid differentiation media.

    How others have used Y-27632 in their research:

    Maintenance of tissue culture of iPSCs; 10 μM Y-27632 for 24 hr; Montefiori et al (2018)Reprogramming of breast cancer cells to induced progenitor-like cells (iPLs) ; 2 μM Y27632 ; Yuan et al (2018)Differentiation - Y-27632 enables human embryonic stem cells to survive and differentiate into cortical and basal telencephalic progenitors; Watanabe et al (2007)

    *Also available in simple stock solutions (ab144494) - add 1 ml of water to get an exact, ready-to-use concentration.

  • Purity

    >99%

  • CAS Number

    129830-38-2

  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride

  • Molecular weight

    320.26

  • Molecular formula

    C14H21N3O.2HCl

  • PubChem identifier

    9901617

  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.

  • Solubility overview

    Soluble in water to 100 mM and in DMSO to 100mM

  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Refer to SDS for further information.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    Cl.Cl.O=C(Nc1ccncc1)[C@@H]2CC[C@H](CC2)[C@@H](C)N

  • Source

    Synthetic

  • Research areas

    • Cell Biology
    • Apoptosis
    • Intracellular
    • Kinases
    • Signal Transduction
    • Cytoskeleton / ECM
    • Cytoskeleton
    • Microfilaments
    • Actin etc
    • Actin Assembly
    • Signal Transduction
    • Protein Phosphorylation
    • Ser / Thr Kinases
    • Other Kinases
    • Signal Transduction
    • Signaling Pathway
    • G Protein Signaling
    • Small G Proteins
    • Ras Family
    • Cell Biology
    • Cell Cycle
    • Cell Division
    • Centromere
    • Cancer
    • Cell cycle
    • Cell division
    • Cancer
    • Signal transduction
    • Protein phosphorylation
    • Serine/threonine kinases
    • Other
    • Biochemicals
    • Product Range
    • Just Add Water
    • Biochemicals
    • Chemical Type
    • Biochemicals
    • Biochemicals
    • Pharmacology
    • Enzymes
    • Kinase
    • Rho kinase
    • Inhibitors
    • Biochemicals
    • Pharmacology
    • Signaling
    • Extracellular matrix & cell adhesion
    • Rho kinase
    • Biochemicals
    • Pharmacology
    • Signaling
    • Stem Cells
    • Other
    • Biochemicals
    • Research Area
    • Cancer
    • Extracellular matrix & cell adhesion
    • Rho kinase
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