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商品描述
| IC50 | 0.2 μM |
|---|---|
| Targets | ATPase |
| Solubility | 4 mg/mL (14.26 mM) in DMSO |
| Other Name | Decumbin, Ascotoxin, Cyanein, Nectrolide, Synergisidin, BFA |
Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus. BFA is an activator of the sphingomyelin cycle. Brefeldin A-mediated apoptosis has been observed in human tumor cells.
Brefeldin A has been shown to increase CRISPR-mediated homology-directed repair (HDR) efficiency.
