ubpbio/GST-USP4/H5410/50微克

价格
¥3900.00
货号:H5410
浏览量:127
品牌:UBPBio
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商品描述
USP4isamemberoftheubiquitin-specificproteasefamilyofdeubiquitinatingenzyme.AnumberofsubstratesofUsp4havebeenidentified,includingTRIM21,TRAF2,TRAF6,RIG-1,RIP1,PDK1,TAK1andetc.Usp4-mediateddeubiquitinationwasfoundtoregulateseveralsignalingpathways,includingtheAKTsignaling,RIG-1-mediatedantiviralresponse,TNFα-inducedsignaling,andtheWntsignaling.

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Usp4isamemberoftheubiquitin-specificproteasefamilyofdeubiquitinatingenzyme.AnumberofsubstratesofUsp4havebeenidentified,includingTRIM21,TRAF2,TRAF6,RIG-1,RIP1,PDK1,TAK1andetc.Usp4-mediateddeubiquitinationwasfoundtoregulateseveralsignalingpathways,includingtheAKTsignaling,RIG-1-mediatedantiviralresponse,TNFα-inducedsignaling,andtheWntsignaling.
Images:(Clickimagetoenlarge)
ProductName:GST-USP4
AlsoKnownAs:UNP;Unph
CatalogNo.:H5410
Size:50µg
MolecularWeight:108.6kDa
Species:Human
Source:Bacterialrecombinant
Stock:20mMTris,150mMNaCl,2mMβME,10%Glycerol
Concentration:Seetubelabel
QualityAssurance:~75%bySDS-PAGE,seedatasheetforgelimage
Storage:Storeat-80°C;avoidmultiplefreeze-thawcycles
PDFDataSheet:PDFDatasheetMSDS
NCBIRefSeq:NM_003363.3
Image(s):
Images:(Clickimagetoenlarge)
Coomassie-stainedSDS-PAGE
Lane1:MolecularweightMarkers
Lane2:5µgpurifiedGST-USP4
ShippingMethod:Dryiceshipping
References:1.WangL,etal.(2013)JVirol.87(8):4507-15.
2.ZhangL,etal.(2012)NatCellBiol.14(7):717-26.
3.XiaoN,etal.(2012)BiochemJ.441(3):979-86.
Coomassie-stainedSDS-PAGE
Lane1:Molecularweightmarkers
Lane2:5µgpurifiedGST-USP4
Ubiquitin-Proteasome Biotechnologies成立于2011年,ubpbio是由科学家和投资者创立的私营企业。ubpbio致力于为学术界和工业界提供高质量的试剂和其他相关产品。ubpbio产品线包括的高度纯化的蛋白酶,E1和E2的酶,泛素和泛素衍生物,蛋白酶体抑制剂和蛋白酶基板。ubpbio不断开发创新以增加新的产品,ubpbio致力为全球的客户提供更多的帮助。在人类细胞中,有超过1000的蛋白质/酶,参与维持泛素-蛋白酶体系统的正常活动。失调的UPS已发现涉及大量的人类疾病包括癌症的病理生理,炎性疾病和神经退行性疾病。ubpbio致力为客户提供更好的泛素-蛋白酶体系统解决方案。