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商品描述
Non-cleavable K63 polyUb chains are made of the Ub(L73P) mutant, this substitution makes the formed polyubiquitin chains to be resistant to the majority of deubiquitinating enzymes.
Additional Information
| Product Name: | Non-cleavable K63 PolyUb Chain (2-10) |
|---|---|
| Also Known As: | N/A |
| Catalog No.: | D2700 |
| Size: | 25 µg |
| Molecular Weight: | N/A |
| Species: | Human |
| Source: | Bacterial recombinant |
| Stock: | 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol |
| Concentration: | See tube label |
| Quality Assurance: | ~95% by SDS-PAGE, see datasheet for gel image |
| Storage: | Store at -80°C; avoid multiple freeze-thaw cycles |
| PDF Data Sheet: | PDF Datasheet， MSDS |
| NCBI RefSeq: | N/A |
| Image(s): | No |
| Shipping Method: | Dry ice shipping |
| References: | 1. Hershko A,et al. (1980) Proc Natl Acad Sci USA 77(4), 1783-1786. 2. Pickart CM, (1997) FASEB 11(13), 1055-1066. 3. Hershko A, et al. (1998) Ann Rev Biochem 67, 425-479. 4. Jiang X, et al. (2012) Nature Reviews Immunology 12, 35-48. |
Details
Non-cleavable K63 polyUb chains are made of the Ub(L73P) mutant, this substitution makes the formed polyubiquitin chains to be resistant to the majority of deubiquitinating enzymes.
Ubiquitin-Proteasome Biotechnologies成立于2011年，ubpbio是由科学家和投资者创立的私营企业。ubpbio致力于为学术界和工业界提供高质量的试剂和其他相关产品。ubpbio产品线包括的高度纯化的蛋白酶，E1和E2的酶，泛素和泛素衍生物，蛋白酶体抑制剂和蛋白酶基板。ubpbio不断开发创新以增加新的产品，ubpbio致力为全球的客户提供更多的帮助。在人类细胞中，有超过1000的蛋白质/酶，参与维持泛素-蛋白酶体系统的正常活动。失调的UPS已发现涉及大量的人类疾病包括癌症的病理生理，炎性疾病和神经退行性疾病。ubpbio致力为客户提供更好的泛素-蛋白酶体系统解决方案。 
