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公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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https://www.ebiomall.com
商品描述
UBE1isanE1enzymewithintheE1,E2,E3cascadewhichconjugatesUbtoproteinsubstrates.UBE1activatesUbbycatalyzinganATP–dependentreaction;UbisconjugatedontothecatalyticCysresidueofUBE1byformationofathioesterbond.TheactivatedUbisthenpassedontoaUb-conjugatingenzymeE2;UbchargedE2bindsaUbligaseE3thatdirectlybindssubstrateproteins.UbistransferredtotheHECTdomainE3spriortobeingconjugatedonsubstrateproteins.ForRINGdomainE3s,UbistransferreddirectlyfromanE2tosubstrateproteins.
AdditionalInformation
| ProductName: | UBE1 | ||
|---|---|---|---|
| AlsoKnownAs: | UBA1;A1S9;A1ST;GXP1;UBE1;A1S9T;AMCX1;POC20;SMAX2;UBA1A;UBE1X | ||
| CatalogNo.: | B1101 | ||
| Size: | 100µg | ||
| MolecularWeight: | 117.8kDa | ||
| Species: | Human | ||
| Source: | Sf21insectcells | ||
| Stock: | 20mMTris,150mMNaCl,2mMβME,10%Glycerol | ||
| Concentration: | Seetubelabel | ||
| QualityAssurance: | ~95%bySDS-PAGE,seedatasheetforgelimage | ||
| Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles | ||
| PDFDataSheet: | PDFDatasheet，MSDS | ||
| NCBIRefSeq: | NM_003334 | ||
| Image(s): | (Clickimagetoenlarge)
| ||
| ShippingMethod: | Dryiceshipping | ||
| References: | 1.HandleyPM,etal.(1991)ProcNatlAcadSciUSA88,258–262. 2.ZhengM,etal.(2009)MolBiolRep37,1413–1419.3.SchulmanBA,etal.(2009)NatRevMolBiol10(5),319–331. |
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| Coomassie-stainedSDS-PAGE Lane1:Molecularweightmarkers Lane2:5µgpurifiedUBE1 |
