Description

ANTIBODYCONCENTRATION
1mg/mlin1XPBScontaining50%glycerol.
ThismonoclonalantibodyisanIgG3affinitypurifiedfrommouseascites.
IMMUNOGEN
PurifiedADP-ribosepolymersbetween2and50unitslong.
SPECIFICITY
PARpolymers2to50unitslong
STORAGE
Storeantibodyat-20°Cinamanualdefrostfreezer.
APPLICATIONS
ELISA,WesternBlotAnalysis,immunoprecipitation,andimmunopurification

PARP1-TDP1couplingfortherepairoftopoisomeraseI-inducedDNAdamage
Das,B.B.,Huang,S.N.,Murai,J.,Rehman,I.,Ame,J.C.,Sengupta,S.,Das,S.K.,Majumdar,P.,Zhang,H.,Biard,D.,Majumder,H.K.,Schreiber,V.,andPommier,Y.,
NucleicAcidsRes.,Feb2014;10.1093/nar/gku088
http://nar.oxfordjournals.org/cgi/content/abstract/gku088v1

ATMpreventsDSBformationbycoordinatingSSBrepairandcellcycleprogression
SvetlanaV.KhoronenkovaandGrigoryL.Dianov
PNAS,Mar2015;112:3997–4002.
http://www.pnas.org/cgi/content/abstract/112/13/3997

“Consequenceofthetumor-associatedconversiontocyclin
D1b”
“MichaelAAugello,LisaDBerman-Booty,RichardCarr,3rd,AkihiroYoshida,JeffryL
Dean,MatthewJSchiewer,FelixYFeng,ScottATomlins,ErheGao,WalterJKoch,
JeffreyLBenovic,JohnAlanDiehl,andKarenEKnudsen”
EMBOMolMed.,May2015;7:628–647.
http://EMBOMolMed.embopress.org/cgi/content/abstract/7/5/628

Poly(ADP-ribosyl)ationofFOXP3ProteinMediatedbyPARP-1ProteinRegulatestheFunctionofRegulatoryTCells
XueruiLuo,JiaNie,ShuaiweiWang,ZuojiaChen,WanJunChen,DanLi,HuiHu,andBinLi
J.Biol.Chem.,Nov2015;290:28675–28682.
http://www.jbc.org/cgi/content/abstract/290/48/28675

Trevigen，Inc.是一家发展迅速的生物技术公司，致力于开发用于癌症研究，药物发现，遗传毒理学，再生医学和干细胞研究的产品和技术。我们提供试剂盒和试剂，用于研究DNA损伤和修复，细胞凋亡，氧化应激，癌细胞行为，3D培养和干细胞。该公司获得了美国国立卫生研究院（National Institutes of Health）多项SBIR资助。