Description

Cultrex®BasementMembraneExtract(BME)isasolubleformofbasementmembranepurifiedfromEngelbreth-Holm-Swarm(EHS)tumor.Thisextractprovidesanaturalextracellularmatrixhydrogelthatpolymerizesat37°Ctoformareconstitutedbasementmembrane.Basementmembranesarecontinuoussheetsofspecializedextracellularmatrixthatformaninterfacebetweenendothelial,epithelial,muscle,orneuronalcellsandtheiradjacentstromaandthatplayanessentialroleintissueorganizationbyinfluencingcelladhesion,migration,proliferation,anddifferentiation.ThemajorcomponentsofBMEincludelaminin,collagenIV,entactin,andheparinsulfateproteoglycans.

TheCultreCoat®24WellBMECoatedCellInvasionAssayprovidesatoolforassessingcellinvasionthroughastandardizedthickcoatingofreconstitutedbasementmembranematrixandisavailableina24wellformat.

Catalog#3480-024-Kincludes:
CatalogNumber	Description	Qty
3480-024-01	CultreCoat®24wellplatewithBMECoatedInserts	1
4892-010-01	CalceinAM	1
3455-096-04	25XCellWashBuffer	1
3455-096-05	10XCellDissociationSolution	1
3480-024-02	20XRehydrationSolutionA	1
3480-024-03	20XRehydrationSolutionB	1

IdentificationofanEGFRvIII-JNK2-HGF/c-Met–SignalingAxisRequiredforIntercellularCrosstalkandGlioblastomaMultiformeCellInvasion
VanessaC.Saunders,MarieLafitte,IsabelAdrados,VictorQuereda,DanielFeurstein,YuanYuanLing,MohammadFallahi,LauraH.Rosenberg,andDerekR.Duckett
Mol.Pharmacol.,Oct2015;88:962–969.
http://molpharm.aspetjournals.org/cgi/content/abstract/88/6/962

Trevigen，Inc.是一家发展迅速的生物技术公司，致力于开发用于癌症研究，药物发现，遗传毒理学，再生医学和干细胞研究的产品和技术。我们提供试剂盒和试剂，用于研究DNA损伤和修复，细胞凋亡，氧化应激，癌细胞行为，3D培养和干细胞。该公司获得了美国国立卫生研究院（National Institutes of Health）多项SBIR资助。