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联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
Specifications
| SPECIES: | Murine |
|---|---|
| SOURCESPECIES: | E.coli |
| SEQUENCE: | DGNTTRTPETNGSLCGAPGENCTGTTPRQKVKTHFSRCPKQYKHYCIHGRCRFVVDEQTPSCICEKGYFGARCERVDLFY |
| TESTEDAPPLICATIONS: | |
| BIOLOGICALACTIVITY: | BiologicalactivitywasdeterminedbyitsABIlitytostimulatetheproliferationofmouseBalb/3T3cells.TheexpectedED50is≤0.01ng/mL,correspondingtoaspecificactivityof≥1x108units/mg.Endotoxinlevelislessthan0.1ngperμg(1EU/μg). |
Properties
| PURITY: | Greaterthan98%bySDS-PAGEgelandHPLCanalyses. |
|---|---|
| PHYSICALSTATE: | Lyophilized |
| STORAGECONDITIONS: | ThelyophilizedBetacellulinrecombinantproteinisstableforatleast2yearsfromdateofreceiptat-20˚C.ReconstitutedBetacellulinstableforatleast3monthswhenstoredinworkingaliquotswithacarrierproteinat-20˚C.Aswithanyprotein,exposingBetacellulinrecombinantproteintorepeatedfreeze/thawcyclesisnotrecommended.Whenworkingwithproteinscareshouldbetakentokeeprecombinantproteinatacoolandstabletemperature. |
AdditionalInfo
| ALTERNATENAMES: | Bcn,Bcn,Probetacellulin,BTC |
|---|---|
| ACCESSIONNO.: | NP_031594.1 |
| PROTEINGINO.: | 6680812 |
Background
| BetacellulinisanEGF-relatedpolypeptidegrowthfactorthatsignalsthroughtheEGFreceptor.Itisproducedinseveraltissues,includingthepancreas,smallintestine,andincertaintumorcells.Betacellulinisapotentmitogenforretinalpigmentepithelialcellsandvascularsmoothmusclecells.Betacellulinisinitiallysynthesizedasaglycosylated32.0kDatransmembraneprecursorprotein,whichisprocessedbyproteolyticcleavagetoproducethematuresequence.RecombinantmurineBetacellulinisa9.0kDamonomericprotein,containing80aminoresidues,whichcomprisesthematureEGFhomologousportionoftheBetacellulinprotein. |


