Prosci/AADAT抗体/48-416/0.05 mg

价格
¥9000.00
货号:48-416
浏览量:95
品牌:ProSci
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商品描述

Specifications

SPECIESREACTIVITY:Gibbon,Gorilla,Human
TESTEDAPPLICATIONS:IHC
APPLICATIONS:AADATantibodycanbeusedinWesternBlotstartingat0.5-2μg/mL,immunohistochemistrystartingat10μg/mL,andimmunoprecipitation.
USERNOTE:Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher.
SPECIFICITY:BLASTanalysisofthepeptideimmunogenshowednohomologywithotherhumanproteins.
IMMUNOGEN:AADATantibodywasraisedagainstapeptidelocatedintheN-TerminalregionofAADAT(Human).
HOSTSPECIES:Rabbit

Properties

PURIFICATION:ImmunoaffinityChromatography
PHYSICALSTATE:Liquid
BUFFER:PBS,0.1%sodiumazide.
STORAGECONDITIONS:StoreAADATantibodyat4˚Cforshorttermapplications.Forlongtermstorage,aliquotand-20˚C.
CLONALITY:Polyclonal
CONJUGATE:Unconjugated

AdditionalInfo

ALTERNATENAMES:AADAT,2-aminoADIpatetransaminase,KAT2,KAT/AadAT,KATII,KynurenineaminotransferaseII,Aminoadipateaminotransferase
ACCESSIONNO.:Q8N5Z0
PROTEINGINO.:46395904
OFFICIALSYMBOL:AADAT
GENEID:51166

Background

BACKGROUND:KynurenineaminotransferasecatalyzestheirreversIBLetransaminationoftheL-tryptophanmetaboliteL-kynureninetoformkynurenicacid.KynurenicacidisanantagoNISTattheglycinesiteofNMDAreceptorsandincreasedlevelsofkynurenicacidarethoughttoexertaneuroprotectiveactioninsomepathologicalconditions.
ProSci 研究计划包括癌症生物标记物发现和中和针对新兴病毒(例如HIV和流感)的抗体开发。ProSci的创新方法研究使用基因工程酵母菌株和糖蛋白模拟HIV-1聚糖衣壳并开发针对HIV-1聚糖的中和抗体,已获得NIH的多项小型企业创新研究(SBIR)资助。其研究项目已获得美国专利商标局授予的发明专利,以及许多同行评审的出版物